SLC30A4 and CLN6

Data Source:
BioGRID (two hybrid)

		SLC30A4	CLN6
Description		solute carrier family 30 member 4	CLN6 transmembrane ER protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane	Nucleolus Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding	Protein Binding Lysophosphatidic Acid Binding Protein Homodimerization Activity Sulfatide Binding
	Biological Process	Response To Toxic Substance Response To Zinc Ion Zinc Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport	Ganglioside Metabolic Process Lysosome Organization Lysosomal Lumen Acidification Visual Perception Cholesterol Metabolic Process Protein Catabolic Process Glycosaminoglycan Metabolic Process Locomotion Involved In Locomotory Behavior Cellular Macromolecule Catabolic Process Positive Regulation Of Proteolysis
Pathways
Drugs
Diseases			Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10) Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075)	Major depressive disorder ( 23377640) Restless legs syndrome ( 29029846)
Interacting Genes		14 interacting genes: BTN2A2 CLN6 CMTM5 FZD7 IER3IP1 LEPROTL1 NSG1 PEDS1-UBE2V1 SERP2 TMEM100 TMEM60 TNF TNFRSF10C YIPF6	26 interacting genes: ARL13B CD79A CISD2 CLDN7 CLEC10A CPLX4 CREB3L1 CYBC1 EBAG9 EVI2B FAM209A FNDC9 GJA8 GORAB KIR2DL3 LIME1 LMNA LRRC25 RIC3 SLC22A23 SLC30A4 STX1A TEX264 TMEM139 TMEM237 TMPRSS2
Entrez ID		7782	54982
HPRD ID		03651	05991
Ensembl ID		ENSG00000104154	ENSG00000128973
Uniprot IDs		O14863	A0A024R601 Q9NWW5
PDB IDs
Enriched GO Terms of Interacting Partners?
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