PEDS1-UBE2V1 and SLC18A3

Data Source:
BioGRID (two hybrid)

		PEDS1-UBE2V1	SLC18A3
Description		PEDS1-UBE2V1 readthrough	solute carrier family 18 member A3
Image			No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Integral Component Of Membrane AP-1 Adaptor Complex AP-2 Adaptor Complex Clathrin-coated Vesicle Membrane Terminal Bouton Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
	Molecular Function		Acetylcholine Transmembrane Transporter Activity Protein Binding Transmembrane Transporter Activity
	Biological Process		Chemical Synaptic Transmission Neurotransmitter Secretion Organic Cation Transport Transmembrane Transport Membrane Organization Acetate Ester Transport
Pathways		NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Interleukin-1 signaling IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 Aggrephagy Aggrephagy TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Antigen processing: Ubiquitination & Proteasome degradation	Acetylcholine Neurotransmitter Release Cycle Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Asthma (childhood onset) ( 31036433)
Interacting Genes		17 interacting genes: AQP6 CNR2 CREB3L1 FAM209A GPR152 PGRMC2 SLC10A1 SLC10A6 SLC18A3 SLC30A4 STOM TMEM31 TMEM52B TMX2 TRAF6 TRHR UBE2N	3 interacting genes: CCDC167 MFF PEDS1-UBE2V1
Entrez ID		387522	6572
HPRD ID		11926	08979
Ensembl ID		ENSG00000124208	ENSG00000187714
Uniprot IDs		A5PLL7 Q13404	Q16572
PDB IDs		2A4D 2C2V 2HLW 6D6I
Enriched GO Terms of Interacting Partners?
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