PEDS1-UBE2V1 and SLC30A4

Data Source:
BioGRID (two hybrid)

		PEDS1-UBE2V1	SLC30A4
Description		PEDS1-UBE2V1 readthrough	solute carrier family 30 member 4
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Integral Component Of Membrane Late Endosome Membrane
	Molecular Function		Zinc Ion Transmembrane Transporter Activity Protein Binding
	Biological Process		Response To Toxic Substance Response To Zinc Ion Zinc Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport
Pathways		NOD1/2 Signaling Pathway TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 CLEC7A (Dectin-1) signaling Interleukin-1 signaling IRAK1 recruits IKK complex IKK complex recruitment mediated by RIP1 Aggrephagy Aggrephagy TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		17 interacting genes: AQP6 CNR2 CREB3L1 FAM209A GPR152 PGRMC2 SLC10A1 SLC10A6 SLC18A3 SLC30A4 STOM TMEM31 TMEM52B TMX2 TRAF6 TRHR UBE2N	14 interacting genes: BTN2A2 CLN6 CMTM5 FZD7 IER3IP1 LEPROTL1 NSG1 PEDS1-UBE2V1 SERP2 TMEM100 TMEM60 TNF TNFRSF10C YIPF6
Entrez ID		387522	7782
HPRD ID		11926	03651
Ensembl ID		ENSG00000124208	ENSG00000104154
Uniprot IDs		A5PLL7 Q13404	O14863
PDB IDs		2A4D 2C2V 2HLW 6D6I
Enriched GO Terms of Interacting Partners?
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