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ZNF24 and NEK6
Data Source:
BioGRID
(two hybrid)
ZNF24
NEK6
Description
zinc finger protein 24
NIMA related kinase 6
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spindle Pole
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Microtubule
Nuclear Speck
Protein-containing Complex
Centriolar Satellite
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Identical Protein Binding
Sequence-specific DNA Binding
Metal Ion Binding
Magnesium Ion Binding
Transcription Corepressor Binding
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinesin Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Activating Transcription Factor Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Regulation Of Transcription By RNA Polymerase II
Myelination
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Apoptotic Process
Chromosome Segregation
Mitotic Nuclear Envelope Disassembly
Regulation Of Mitotic Cell Cycle
Peptidyl-serine Phosphorylation
Regulation Of Mitotic Metaphase/anaphase Transition
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Protein Autophosphorylation
Spindle Assembly
Cell Division
Regulation Of Cellular Senescence
Pathways
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Asthma (
32296059
)
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Blond vs. brown/black hair color (
30531825
)
Chronotype (
30696823
)
Cognitive performance (
20125193
)
Free thyroxine concentration (
30367059
)
Heel bone mineral density (
30598549
)
Medication use (thyroid preparations) (
31015401
)
Mercury levels (
26025379
)
Neurociticism (
29500382
)
Pulse pressure (
30224653
)
Thyroid stimulating hormone levels (
32769997
)
Vitiligo (
27723757
)
Interacting Genes
54 interacting genes:
APLP1
CCDC130
CEP126
COPS6
CRMP1
DDX6
DZIP3
EEF1A1
EEF1G
ERG28
FAM161A
FANCA
HAP1
HMGB1
KAT5
LMO1
LMO2
LRIF1
MAP1LC3C
MID2
MZF1
NEK6
PPP1CC
PRPF31
RBM48
SCAND1
SEC62
SETDB1
TCAF1
TP53
TRIM25
TRIM41
UBE2I
UNC119
UTP14A
ZBTB16
ZGPAT
ZKSCAN4
ZKSCAN8
ZNF165
ZNF174
ZNF232
ZNF396
ZNF410
ZNF444
ZNF446
ZNF620
ZNHIT3
ZSCAN12
ZSCAN16
ZSCAN21
ZSCAN22
ZSCAN23
ZSCAN32
117 interacting genes:
ANKRA2
ARHGAP33
ARRB1
ATF4
BEND7
BHLHE40
CBY2
CCDC120
CCDC136
CCDC85B
CDC42
CDK7
CEP76
CFP
CIR1
COG6
CTBP2
DDIT4L
DES
DPH2
EFHC2
ERCC6L2
FAM220A
FHL5
FOXJ3
GFAP
GIGYF1
GLIS3
GOLGA6L2
GRIP1
HOMEZ
HOOK2
HOXA1
HOXB6
HSD17B14
IHO1
IKZF1
IKZF3
INCA1
KATNBL1
KCTD5
KIAA1328
KRT31
KRT34
KRT40
KRT75
KRT8
KRTAP10-8
KRTAP13-1
KRTAP13-3
LNX1
LZTS1
LZTS2
MBD3L1
MEOX2
METTL15
MYOG
MYOZ3
NECAB2
NEFL
NEK9
NIF3L1
NUDT16L1
PAK6
PBX4
PHF1
PICK1
PIN1
PLEKHA7
PPP1R16A
PRAM1
PRDM16
PRDM6
PRDX3
PRICKLE4
PTN
PTPN21
PTPRD
RBAK
RBBP6
RIMBP3C
RPS6KB1
RPS7
SAXO1
SGK1
SH3RF2
SMAD4
SMUG1
SMURF2
SORBS3
SPRY3
TASOR2
TCF12
TCF4
TEPSIN
TEX45
TFIP11
TGFBR1
TLE5
TNK2
TRAF2
TRIM23
TRIM27
TRIM54
TRIP4
UBXN11
XIAP
ZC2HC1C
ZCCHC7
ZFP90
ZNF24
ZNF343
ZNF438
ZNF587
ZNF688
ZNF774
ZRANB1
Entrez ID
7572
10783
HPRD ID
01921
05348
Ensembl ID
ENSG00000172466
ENSG00000119408
Uniprot IDs
P17028
A0A024R8A6
Q9HC98
PDB IDs
1X6E
3LHR
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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