FUBP1 and SNRPC

Data Source:
BioGRID (two hybrid)

		FUBP1	SNRPC
Description		far upstream element binding protein 1	small nuclear ribonucleoprotein polypeptide C
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Commitment Complex Nucleoplasm U1 SnRNP Cajal Body U2-type Prespliceosome
	Molecular Function	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding	RNA Binding Single-stranded RNA Binding MRNA Binding Protein Binding Zinc Ion Binding U1 SnRNA Binding Pre-mRNA 5'-splice Site Binding Protein Homodimerization Activity
	Biological Process	Regulation Of Gene Expression Positive Regulation Of Gene Expression	Spliceosomal SnRNP Assembly MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs		Irofulven Sacituzumab govitecan
Diseases
GWAS		BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Lung cancer in never smokers ( 28604730) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Psoriasis ( 28537254)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol ( 25961943) Low density lipoprotein cholesterol levels ( 32154731) Obese vs. thin ( 30677029) Refractive error ( 32231278) Systemic lupus erythematosus ( 24871463)
Interacting Genes		25 interacting genes: AIMP2 ANXA11 CCNH CELF1 CHD3 CRMP1 ESR1 GTF2H1 IMMT MAPK1IP1L MYOC PRPF40B PRR13 PUF60 SIRPA SMN1 SMURF2 SNRPA SNRPB SNRPC TIAL1 TLE1 U2AF2 VIM VPS37C	82 interacting genes: AGGF1 AKAP8L ANKRD10 ARHGAP9 BAG4 BCAS2 BOLL C19orf54 CREM CYSRT1 DAZAP2 DDX42 ECM1 EWSR1 EXOSC8 EYA2 FAM168A FAM168B FHL3 FUBP1 GIGYF1 GOLGA2 HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH2 HNRNPUL1 HOXA1 HSD17B14 ILF3 INTS11 JMJD7 KHDRBS3 KLF1 KRTAP11-1 KRTAP13-2 KRTAP19-2 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP22-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 MAGED1 METTL27 MGAT5B MKRN3 NCAPH2 NCKIPSD ODAM PLA2G10 PRDM14 PRR20A PRR20B PRR20C PRR20D PRR20E PSMA3 RAMAC RBFOX2 RBM11 RBM4 RBPMS RERE RFX6 RNF31 RUNX1 SEC23B SNRNP70 SPAG8 SS18L1 STH TENT5A TLE5 TRIB3 UFSP1 WDR77 WWOX WWP2
Entrez ID		8880	6631
HPRD ID		10349	04630
Ensembl ID		ENSG00000162613	ENSG00000124562
Uniprot IDs		A0A384MDX9 B4DT31 Q96AE4	P09234 Q5TAL4
PDB IDs		1J4W 2KXH 4LIJ 6Y24 6Y2C 6Y2D	2VRD 3CW1 4PJO 6ELD 6QX9
Enriched GO Terms of Interacting Partners?
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