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TSPO and LEUTX
Data Source:
BioGRID
(two hybrid)
TSPO
LEUTX
Description
translocator protein
leucine twenty homeobox
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Cytosol
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Chromatin
Nucleus
Molecular Function
Androgen Binding
Protein Binding
Benzodiazepine Receptor Activity
Cholesterol Binding
Ion Channel Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Protein Binding
Biological Process
Protein Targeting To Mitochondrion
C21-steroid Hormone Biosynthetic Process
Heme Biosynthetic Process
Anion Transport
Chloride Transport
Lipid Transport
Aging
Steroid Metabolic Process
Glial Cell Migration
Response To Manganese Ion
Response To Vitamin B1
Positive Regulation Of Necrotic Cell Death
Peripheral Nervous System Axon Regeneration
Adrenal Gland Development
Negative Regulation Of Protein Ubiquitination
Regulation Of Cholesterol Transport
Response To Progesterone
Negative Regulation Of Tumor Necrosis Factor Production
Response To Testosterone
Regulation Of Cell Population Proliferation
Response To Drug
Positive Regulation Of Apoptotic Process
Negative Regulation Of Nitric Oxide Biosynthetic Process
Behavioral Response To Pain
Regulation Of Steroid Biosynthetic Process
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Calcium Ion Transport
Contact Inhibition
Positive Regulation Of Glial Cell Proliferation
Negative Regulation Of Glial Cell Proliferation
Cellular Response To Lipopolysaccharide
Cellular Response To Zinc Ion
Cellular Hypotonic Response
Maintenance Of Protein Location In Mitochondrion
Negative Regulation Of Autophagy Of Mitochondrion
Negative Regulation Of ATP Metabolic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Pathways
Pregnenolone biosynthesis
Drugs
Chlormezanone
Zopiclone
Diseases
GWAS
Metabolite levels (
23823483
)
Monocyte count (
27863252
)
Monocyte percentage of white cells (
32888494
27863252
)
White blood cell count (
32888494
)
Macular thickness (
30535121
)
Interacting Genes
17 interacting genes:
AMIGO1
CLEC10A
CREB3L1
DBI
FAM209A
FCER1G
ICAM3
KCNF1
LEUTX
LHFPL5
LYPD5
MEOX2
NCR3LG1
PVR
TMEM14B
TMEM9
TSPOAP1
46 interacting genes:
AGPAT4
AIG1
AQP2
AQP3
ASGR1
C1GALT1
C1QL4
C3orf52
CDS2
CMTM3
CMTM5
CNIH1
CNIH3
CXCL9
EMP3
ENTPD3
FAM24B
FZD7
GOSR2
KIR2DL3
LAT
MRPL57
MS4A1
NAPB
NDRG4
OLFM4
PLP1
PNLIPRP1
PRB1
SLC13A3
SLC30A8
SLC41A2
STATH
TF
TMEM128
TMEM147
TMEM187
TMEM254
TMEM60
TMEM97
TSPO
TTPA
UNC93B1
VAMP4
ZFPL1
ZNF646
Entrez ID
706
342900
HPRD ID
15913
Ensembl ID
ENSG00000100300
ENSG00000213921
Uniprot IDs
O76068
P30536
A8MZ59
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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