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TSPO and LYPD5
Data Source:
BioGRID
(two hybrid)
TSPO
LYPD5
Description
translocator protein
LY6/PLAUR domain containing 5
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Endoplasmic Reticulum
Cytosol
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Extracellular Region
Plasma Membrane
Anchored Component Of Membrane
Molecular Function
Androgen Binding
Protein Binding
Benzodiazepine Receptor Activity
Cholesterol Binding
Ion Channel Binding
Protein Binding
Laminin Binding
Biological Process
Protein Targeting To Mitochondrion
C21-steroid Hormone Biosynthetic Process
Heme Biosynthetic Process
Anion Transport
Chloride Transport
Lipid Transport
Aging
Steroid Metabolic Process
Glial Cell Migration
Response To Manganese Ion
Response To Vitamin B1
Positive Regulation Of Necrotic Cell Death
Peripheral Nervous System Axon Regeneration
Adrenal Gland Development
Negative Regulation Of Protein Ubiquitination
Regulation Of Cholesterol Transport
Response To Progesterone
Negative Regulation Of Tumor Necrosis Factor Production
Response To Testosterone
Regulation Of Cell Population Proliferation
Response To Drug
Positive Regulation Of Apoptotic Process
Negative Regulation Of Nitric Oxide Biosynthetic Process
Behavioral Response To Pain
Regulation Of Steroid Biosynthetic Process
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Calcium Ion Transport
Contact Inhibition
Positive Regulation Of Glial Cell Proliferation
Negative Regulation Of Glial Cell Proliferation
Cellular Response To Lipopolysaccharide
Cellular Response To Zinc Ion
Cellular Hypotonic Response
Maintenance Of Protein Location In Mitochondrion
Negative Regulation Of Autophagy Of Mitochondrion
Negative Regulation Of ATP Metabolic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Cell-matrix Adhesion
Pathways
Pregnenolone biosynthesis
Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Chlormezanone
Zopiclone
Diseases
GWAS
Metabolite levels (
23823483
)
Monocyte count (
27863252
)
Monocyte percentage of white cells (
32888494
27863252
)
White blood cell count (
32888494
)
Breast cancer (
29059683
23535729
)
Reading or mathematical ability (
25003214
)
Interacting Genes
17 interacting genes:
AMIGO1
CLEC10A
CREB3L1
DBI
FAM209A
FCER1G
ICAM3
KCNF1
LEUTX
LHFPL5
LYPD5
MEOX2
NCR3LG1
PVR
TMEM14B
TMEM9
TSPOAP1
8 interacting genes:
BET1
EHHADH
ERG28
ERMP1
IFITM3
NINJ2
PLPPR2
TSPO
Entrez ID
706
284348
HPRD ID
15913
08084
Ensembl ID
ENSG00000100300
ENSG00000159871
Uniprot IDs
O76068
P30536
Q6UWN5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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