LEUTX and AQP3

Data Source:
BioGRID (two hybrid)

		LEUTX	AQP3
Description		leucine twenty homeobox	aquaporin 3 (Gill blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleoplasm Cytoplasm Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	Protein Binding Urea Transmembrane Transporter Activity Water Channel Activity Glycerol Channel Activity Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Positive Regulation Of Immune System Process Renal Water Homeostasis Water Transport Glycerol Transport Response To Retinoic Acid Response To Vitamin D Odontogenesis Regulation Of Keratinocyte Differentiation Response To Calcium Ion Renal Water Absorption Cellular Response To Hypoxia Urea Transmembrane Transport Cellular Response To Oxygen-glucose Deprivation
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins Passive transport by Aquaporins
Drugs			Sennosides
Diseases
GWAS		Macular thickness ( 30535121)	Lung adenocarcinoma ( 28604730 31326317) Neuroblastoma or malignant cutaneous melanoma ( 31605138)
Interacting Genes		46 interacting genes: AGPAT4 AIG1 AQP2 AQP3 ASGR1 C1GALT1 C1QL4 C3orf52 CDS2 CMTM3 CMTM5 CNIH1 CNIH3 CXCL9 EMP3 ENTPD3 FAM24B FZD7 GOSR2 KIR2DL3 LAT MRPL57 MS4A1 NAPB NDRG4 OLFM4 PLP1 PNLIPRP1 PRB1 SLC13A3 SLC30A8 SLC41A2 STATH TF TMEM128 TMEM147 TMEM187 TMEM254 TMEM60 TMEM97 TSPO TTPA UNC93B1 VAMP4 ZFPL1 ZNF646	28 interacting genes: C14orf180 CD79A ERG28 ERGIC3 EVI2B FAM209A GIMAP5 GPR152 GPX8 HIBADH LEUTX LMNA MFF MGST3 MRM1 MUC1 OLFM4 PLD2 PLP2 SAR1A SGPL1 SSMEM1 STX1A TMEM107 TMEM42 TMEM86A TNF VASN
Entrez ID		342900	360
HPRD ID			08970
Ensembl ID		ENSG00000213921	ENSG00000165272
Uniprot IDs		A8MZ59	A0A2R8Y2R4 Q92482
PDB IDs
Enriched GO Terms of Interacting Partners?
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