TSPO and DBI

Data Source:
HPRD (in vivo, in vitro)

		TSPO	DBI
Description		translocator protein	diazepam binding inhibitor, acyl-CoA binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Integral Component Of Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Endoplasmic Reticulum Lumen Golgi Apparatus Protein-lipid Complex Extracellular Exosome
	Molecular Function	Androgen Binding Protein Binding Benzodiazepine Receptor Activity Cholesterol Binding Ion Channel Binding	Lipid Binding Benzodiazepine Receptor Binding Long-chain Fatty Acyl-CoA Binding Identical Protein Binding
	Biological Process	Protein Targeting To Mitochondrion C21-steroid Hormone Biosynthetic Process Heme Biosynthetic Process Anion Transport Chloride Transport Lipid Transport Aging Steroid Metabolic Process Glial Cell Migration Response To Manganese Ion Response To Vitamin B1 Positive Regulation Of Necrotic Cell Death Peripheral Nervous System Axon Regeneration Adrenal Gland Development Negative Regulation Of Protein Ubiquitination Regulation Of Cholesterol Transport Response To Progesterone Negative Regulation Of Tumor Necrosis Factor Production Response To Testosterone Regulation Of Cell Population Proliferation Response To Drug Positive Regulation Of Apoptotic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Regulation Of Steroid Biosynthetic Process Positive Regulation Of Mitochondrial Depolarization Positive Regulation Of Calcium Ion Transport Contact Inhibition Positive Regulation Of Glial Cell Proliferation Negative Regulation Of Glial Cell Proliferation Cellular Response To Lipopolysaccharide Cellular Response To Zinc Ion Cellular Hypotonic Response Maintenance Of Protein Location In Mitochondrion Negative Regulation Of Autophagy Of Mitochondrion Negative Regulation Of ATP Metabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process	Acyl-CoA Metabolic Process Phosphatidylcholine Acyl-chain Remodeling Negative Regulation Of Protein Lipidation Positive Regulation Of CoA-transferase Activity Positive Regulation Of Phospholipid Transport
Pathways		Pregnenolone biosynthesis	Mitochondrial Fatty Acid Beta-Oxidation
Drugs		Chlormezanone Zopiclone	Coenzyme A Hexadecanal
Diseases
GWAS		Metabolite levels ( 23823483) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) White blood cell count ( 32888494)	Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: AMIGO1 CLEC10A CREB3L1 DBI FAM209A FCER1G ICAM3 KCNF1 LEUTX LHFPL5 LYPD5 MEOX2 NCR3LG1 PVR TMEM14B TMEM9 TSPOAP1	14 interacting genes: CYSLTR2 DDIT4L DUSP23 GSK3B LAMTOR5 MAP1LC3B NIPSNAP1 NSFL1C PFDN2 PPCDC RAD23A RAD23B TSPO UBXN2A
Entrez ID		706	1622
HPRD ID		15913	08832
Ensembl ID		ENSG00000100300	ENSG00000155368
Uniprot IDs		O76068 P30536	A0A024RAF2 B8ZWD1 B8ZWD8 P07108
PDB IDs			2CB8 2FJ9
Enriched GO Terms of Interacting Partners?
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