Description |
transforming growth factor beta receptor 1 |
phosphoinositide-3-kinase regulatory subunit 1 |
Image |
|
|
Cellular Component |
|
|
Molecular Function |
|
|
Biological Process |
|
|
Pathways |
|
|
Drugs |
|
|
Diseases |
|
|
GWAS |
- Advanced age-related macular degeneration ( 26691988)
- Age-related macular degeneration ( 23455636)
- Asthma ( 31959851 32296059)
- Callous-unemotional behaviour ( 23874384)
- Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
- Dental caries ( 23064961)
- Epithelial ovarian cancer ( 25134534)
- Fractures (paediatric) ( 32742401)
- Gestational age at birth (maternal effect) ( 28877031)
- Refractive error ( 32231278)
- Spherical equivalent or myopia (age of diagnosis) ( 29808027)
|
|
Interacting Genes |
163 interacting genes:
ACVR1
ACVRL1
AMHR2
ANAPC5
AP2B1
ARHGAP15
ARHGAP31
ARHGEF6
ARL4D
ARL8B
ASH2L
AURKB
BAMBI
BMPR1B
BMPR2
BTBD2
CAV1
CD44
CDC20
CDC42EP4
CDK14
CDK17
CDK4
CDK6
CDKL1
CHN1
CHN2
CHUK
CLU
CSNK1A1
CSNK2A2
CTNNB1
CUL5
DAB2
DAPK2
DCAF12
DCAF6
DUSP13
EIF2AK4
ENC1
ENG
FANCL
FBXL12
FBXO34
FKBP1A
FKBP1B
FNTA
GNA13
GNB2
GNB3
IKBKB
ITK
KATNB1
KCNK18
KLHL1
KLHL35
LIMS1
MAP3K20
MAP3K7
MYO3A
MYOC
MYT1L
NAT8
NEK6
NEK8
NKIRAS1
NRP1
NUAK2
NUP37
OSR1
OTUB1
OXSR1
PAK1
PARD6A
PIK3R1
PIK3R2
PLEK
PLEKHB1
PLEKHJ1
PLK4
PML
POMK
PPP2R2A
PPP3CC
PPP6C
PREB
PREX2
PRPF4
PSMD14
RAB13
RAB25
RAB33B
RAB34
RAB38
RAB3B
RAB6B
RAN
RAP2A
RASD2
RASL12
RGS19
RHEBL1
RHOA
RHOD
RHOG
RHOH
RHOJ
RHPN2
RNF130
RNF146
RNF5
RPAP3
RPS27A
RRH
RTKN
SAMD8
SAT2
SKAP2
SKI
SMAD1
SMAD2
SMAD3
SMAD4
SMAD6
SMAD7
SMURF2
SNTG1
SNX6
SOCS6
SQSTM1
STK35
STRAP
STUB1
STX8
STYXL1
TGFB1
TGFB2
TGFB3
TGFBR2
TGFBRAP1
TNNT1
TRAF6
TRAP1
TSC22D1
TSSK1B
TSSK4
TTC1
TTC27
TTPAL
UBA52
UBB
UBD
UBE2E3
UBE2Z
UBXN1
USP2
USP45
VEPH1
WDR13
WDR33
WDR61
XIAP
ZFYVE9
|
175 interacting genes:
ABL1
ADAM12
ADAMTS2
AGAP2
AKT1
ALK
ANK3
APPL1
AR
ARAF
ARHGAP1
ARHGAP17
ARHGAP32
AXL
BCAR1
BLK
BRCA1
CBL
CBLB
CCL14
CD19
CD22
CD28
CD2AP
CD3E
CD4
CD40
CD5
CD7
CDC42
CDH2
CHRNA7
CLNK
CRK
CRKL
CSF1R
CSF2RA
CTLA4
CTNNB1
CXCL2
CYP4A11
DLX2
DNM1
DOK1
EGF
EGFR
ENKUR
EPHA2
EPOR
ERAS
ERBB2
ERBB3
ERBB4
ESR1
EZR
FASLG
FCGR2A
FER
FES
FGFR1
FLT1
FYN
GAB1
GAB2
GAB3
GHR
GP1BA
GRB2
GSPT1
GTF2H1
HCK
HCST
HGS
HOXA1
HRAS
HTT
IFNAR1
IGF1R
IKZF3
IL13
IL1R1
IL1RAP
IL2RB
IL7R
INPP4A
INSR
IRS1
IRS2
IRS4
ITSN1
JAK1
JAK2
JAK3
KBTBD2
KHDRBS1
KIT
LAT
LCK
LNX2
LRRK2
MAPK8
MAPT
MET
MME
MST1R
MYO16
NFKBIA
NTRK1
NTRK2
NUP85
NYAP1
NYAP2
PASK
PDE4D
PDGFB
PDGFRA
PDGFRB
PECAM1
PFN1
PIK3AP1
PIK3CA
PIK3CB
PIK3CD
PPM1A
PRMT8
PROM1
PSEN1
PSMB5
PTK2
PTK2B
PTPN11
PTPN6
RAC1
RASA1
RASD2
RB1
RET
RRAS2
SH3KBP1
SHB
SHC1
SLC9A2
SOCS1
SOCS6
SOCS7
SQSTM1
SRC
SSTR2
STAT3
SYK
SYN1
TEC
TEK
TGFBR1
TGFBR2
TIE1
TLR2
TNS4
TOM1L1
TRAT1
TSHR
TTR
TUB
TUBA1B
TUBG1
TXK
TYK2
TYRO3
VAV1
VAV3
WAS
WASF3
WBP11
YWHAG
YWHAZ
|
Entrez ID |
7046 |
5295 |
HPRD ID |
01822 |
01381 |
Ensembl ID |
ENSG00000106799
|
ENSG00000145675
|
Uniprot IDs |
B4DXN7
B4DY26
P36897
Q5T7S2
|
A0A2X0SFG1
P27986
|
PDB IDs |
1B6C
1IAS
1PY5
1RW8
1TBI
1VJY
2L5S
2PJY
2WOT
2WOU
2X7O
3FAA
3GXL
3HMM
3KCF
3KFD
3TZM
4X0M
4X2F
4X2G
4X2J
4X2K
4X2N
5E8S
5E8T
5E8U
5E8W
5E8X
5E8Z
5E90
5FRI
5QIK
5QIL
5QIM
5QTZ
5QU0
5USQ
6B8Y
6MAC
|
1A0N
1AZG
1H9O
1PBW
1PHT
1PIC
1PKS
1PKT
2IUG
2IUH
2IUI
2RD0
2V1Y
3HHM
3HIZ
3I5R
3I5S
4A55
4JPS
4L1B
4L23
4L2Y
4OVU
4OVV
4WAF
4YKN
4ZOP
5AUL
5FI4
5GJI
5ITD
5M6U
5SW8
5SWG
5SWO
5SWP
5SWR
5SWT
5SX8
5SX9
5SXA
5SXB
5SXC
5SXD
5SXE
5SXF
5SXI
5SXJ
5SXK
5UBT
5UK8
5UKJ
5UL1
5VLR
5XGH
5XGI
5XGJ
6NCT
6PYR
6PYU
|
Enriched GO Terms of Interacting Partners? |
|
|
Tagcloud ? |
|
|
Tagcloud (Difference) ? |
|
|
Tagcloud (Intersection) ? |
|