TFF3 and PCBD1

Data Source:
BioGRID (two hybrid)

		TFF3	PCBD1
Description		trefoil factor 3	pterin-4 alpha-carbinolamine dehydratase 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding
	Biological Process	Maintenance Of Gastrointestinal Epithelium	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated
Pathways		Estrogen-dependent gene expression	Phenylalanine metabolism
Drugs			L-erythro-7,8-dihydrobiopterin
Diseases			Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Spatial memory ( 31596458)	Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: PCBD1 SGTA UBQLN2 ZSCAN9	54 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KANK2 KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 PICK1 POLR3A PSMA1 RBL2 RPS24 SAP30 SCMH1 SDCBP SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714
Entrez ID		7033	5092
HPRD ID		02797	00523
Ensembl ID		ENSG00000160180	ENSG00000166228
Uniprot IDs		Q07654	P61457
PDB IDs		1E9T 1PE3 6V1C
Enriched GO Terms of Interacting Partners?
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