TEAD3 and PIDD1

Data Source:
BioGRID (two hybrid)

		TEAD3	PIDD1
Description		TEA domain transcription factor 3	p53-induced death domain protein 1
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GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding DNA-binding Transcription Factor Activity Protein Binding	Endopeptidase Activity Death Receptor Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Hippo Signaling Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Asymmetric Neuroblast Division	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Autoprocessing Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription	TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS		Birth weight ( 31043758) Colorectal cancer or advanced adenoma ( 30510241) Offspring birth weight ( 31043758)	Breast cancer ( 29059683)
Interacting Genes		15 interacting genes: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 VGLL3 VGLL4 WWTR1 YAP1	15 interacting genes: AFP CASP2 CCDC85B CRADD EFEMP2 FADD HSD17B14 KHDC4 MADD MAFG MDFI MTNR1B POGZ SOX8 TEAD3
Entrez ID		7005	55367
HPRD ID		04411	11284
Ensembl ID		ENSG00000007866	ENSG00000177595
Uniprot IDs		Q99594	Q9HB75
PDB IDs		5EMW	2OF5
Enriched GO Terms of Interacting Partners?
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