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PIDD1
Description
p53-induced death domain protein 1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Molecular Function
Endopeptidase Activity
Death Receptor Binding
Protein Binding
Biological Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cellular Response To DNA Damage Stimulus
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Protein Autoprocessing
Regulation Of Apoptotic Process
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS
Breast cancer (
29059683
)
Interacting Genes
15 interacting genes:
AFP
CASP2
CCDC85B
CRADD
EFEMP2
FADD
HSD17B14
KHDC4
MADD
MAFG
MDFI
MTNR1B
POGZ
SOX8
TEAD3
Entrez ID
55367
HPRD ID
11284
Ensembl ID
ENSG00000177595
Uniprot IDs
Q9HB75
PDB IDs
2OF5
Enriched GO Terms of Interacting Partners
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