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EMP1 and CEP70
Data Source:
BioGRID
(two hybrid)
EMP1
CEP70
Description
epithelial membrane protein 1
centrosomal protein 70
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Centrosome
Cytosol
Molecular Function
Protein Binding
Protein Binding
Identical Protein Binding
Gamma-tubulin Binding
Biological Process
Cell Death
Epidermis Development
Bleb Assembly
G2/M Transition Of Mitotic Cell Cycle
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Microtubule Cytoskeleton Organization
Ciliary Basal Body-plasma Membrane Docking
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Diseases
GWAS
Coronary artery calcification (
23870195
)
Degraded stimulus continuous performance test score (
31596458
)
Estimated glomerular filtration rate after 1 year in renal transplantation (donor effect) (
30920136
)
Heel bone mineral density (
30598549
28869591
)
Household income (MTAG) (
31844048
)
Refractive error (
32231278
)
Serum albumin level (
29403010
)
Exhaled carbon monoxide levels in smokers with chronic obstructive pulmonary disease (
29631575
)
Male-pattern baldness (
28196072
)
Interacting Genes
61 interacting genes:
ANK1
ANKS6
APOL2
AQP6
ARL13B
ARL6IP1
ASGR2
ATP6V0B
ATP6V0E1
BTN2A2
CCR5
CD37
CD3G
CD53
CD79A
CEP70
CLDN9
CORIN
CXCR2
EBP
EDA
EHHADH
ERGIC3
FFAR2
GIMAP5
GPR42
GPRC5D
HTR2C
ISLR2
JPH1
KLRC1
LAPTM4B
LEPROTL1
LHFPL5
LPAR6
LRRC3B
LSMEM2
MAL
MALL
MS4A7
OPRM1
PLEKHB2
PMP22
RABAC1
RPRM
SERTM1
SMIM3
SPACA1
STOM
SYNE4
TBXA2R
TEX264
TLCD4
TMEM114
TMEM160
TMEM218
TMEM239
TMEM262
TMEM31
TMEM9
TSPO2
242 interacting genes:
ABT1
AGBL2
AKAP17A
ARHGEF3
ARMCX1
ATP5PO
ATXN7
BARD1
BAZ2B
BEX2
BRD1
BRMS1
BRMS1L
BRPF1
BYSL
C1orf35
C7orf25
C8orf33
CARD9
CAVIN3
CBX8
CCDC187
CCDC85B
CDC37
CDC73
CDCA7L
CEP57L1
CFAP53
CLPB
COIL
CWF19L2
DAXX
DAZAP2
DDX41
DDX6
DNAJB11
DNTTIP2
DVL3
EAF1
EBNA1BP2
EIF3D
ELOA
ELOA2
EMD
EMP1
ENKD1
ERCC3
FAM118B
FAM124A
FAM133A
FAM13C
FAM161A
FAM161B
FAM214B
FAM90A1
GADD45GIP1
GAS8
GATAD2B
GCC1
GEM
GLYCTK
GPATCH2L
GPATCH4
GPX7
GSE1
HAUS1
HDAC4
HDAC6
HIC2
HMGB4
HOXB5
HOXC8
HSPD1
IK
INO80B
INPP5J
IPCEF1
IQCE
IQUB
ITPKB
KANK2
KANSL1
KAT14
KAT5
KAT7
KDM1A
KRI1
KRT31
LAMTOR5
LCOR
LENG1
LENG8
LIN37
LNX1
MAB21L2
MAGOH
MBD3
MCM10
MCRS1
MEST
METTL17
MFAP1
MKRN3
MRPL44
NEBL
NIPSNAP3A
NKAP
NKAPD1
NOL12
NOP2
NOP53
NOXA1
NRIP1
NTAQ1
NUSAP1
ODAD4
PAM16
PIBF1
PIMREG
PKN1
PLA2G2A
PPFIA1
PPIG
PPP1R16B
PPP1R18
PRKRIP1
PRPF18
PRPF3
PRPF31
PSMA1
PSORS1C2
RASSF10
RBM10
RCOR3
RHPN1
RNF169
RNF6
RPL13
SCNM1
SEC14L1
SERPINH1
SETD5
SFR1
SH2D4A
SLU7
SMARCE1
SNRPD2
SNW1
SOD2
SPANXN3
SRGN
SSX3
STK25
STMN2
SUV39H1
SUV39H2
SYT17
SYTL4
SYTL5
TAF1D
TBC1D22B
TBC1D30
TCAF1
TCEANC
TEAD4
TLK2
TRAF3IP3
TRIM29
TRIM3
TRIM42
TSFM
TSGA10IP
TSHZ3
TTLL10
TXLNB
TXN2
USP2
UTP11
UTP14A
UTP14C
UTP25
UTP3
VXN
WT1
YJU2
ZBTB16
ZBTB24
ZBTB4
ZBTB47
ZBTB48
ZBTB49
ZBTB8A
ZCCHC10
ZFC3H1
ZFHX3
ZFP1
ZFP91
ZGPAT
ZNF136
ZNF140
ZNF148
ZNF165
ZNF169
ZNF17
ZNF20
ZNF202
ZNF227
ZNF239
ZNF264
ZNF266
ZNF302
ZNF329
ZNF35
ZNF366
ZNF408
ZNF410
ZNF417
ZNF426
ZNF433
ZNF439
ZNF490
ZNF491
ZNF555
ZNF557
ZNF572
ZNF574
ZNF578
ZNF587
ZNF599
ZNF607
ZNF648
ZNF669
ZNF688
ZNF696
ZNF775
ZNF777
ZNF785
ZNF835
ZNF860
ZSCAN12
ZSCAN21
ZSCAN23
Entrez ID
2012
80321
HPRD ID
11892
16779
Ensembl ID
ENSG00000134531
ENSG00000114107
Uniprot IDs
A0A024RAT0
P54849
A0A140VJG2
B7Z2D2
Q8NHQ1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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