ZDHHC15 and CYB5R3

Data Source:
BioGRID (two hybrid)

		ZDHHC15	CYB5R3
Description		zinc finger DHHC-type palmitoyltransferase 15	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Golgi Apparatus Postsynaptic Density Integral Component Of Golgi Membrane Postsynapse	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen Nitric-oxide Synthase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding Nitrite Reductase (NO-forming) Activity NAD Binding FAD Binding
	Biological Process	Protein Targeting To Membrane Synaptic Vesicle Maturation Protein Phosphopantetheinylation Peptidyl-L-cysteine S-palmitoylation Protein Palmitoylation Regulation Of Dendritic Spine Morphogenesis Protein Localization To Postsynapse Protein Localization To Membrane Protein Targeting To Golgi Apparatus Positive Regulation Of Dendrite Development	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation
Pathways			Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases		Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)	Methemoglobinemia
GWAS			Initial pursuit acceleration ( 29064472)
Interacting Genes		48 interacting genes: ADCYAP1R1 ARL13B BNIP3 C14orf180 CD79A CELA2B CERCAM CLEC10A CLRN1 CREB3L1 CYB5R3 DHRSX ERGIC3 FAM241B GIMAP1 GOLGA7B GPR152 LEMD1 LEPROTL1 LHFPL5 LMNA LSMEM1 MCEMP1 MTIF3 ORMDL1 ORMDL2 PEX16 PLLP PRAF2 PVR RUSF1 SLC10A6 SMIM1 SNORC STX3 TBXA2R TMEFF2 TMEM120B TMEM128 TMEM14C TMEM222 TMEM42 TMEM52B TNFRSF10B TSNARE1 TUFM VAPB YIPF4	61 interacting genes: ADAM33 AGTRAP AIG1 ALG8 AQP6 ASGR1 BNIP2 CDIPT CERS4 CNIH1 COL8A2 CSGALNACT2 CYB5A CYCS ELOVL4 FAM210B FAM3C FAXDC2 FUNDC2 FXYD3 GAST GPR152 GRM2 HBG2 HSD17B13 LAPTM5 LRCH4 MFSD6 NINJ1 NRM NSG1 NXPE3 ORMDL2 PNLIPRP1 REEP4 SLC10A1 SLC10A6 SLC13A3 SLC22A2 SLC35A4 SLC35B2 SLC38A7 SPP1 STOM TMEM115 TMEM14B TMEM14C TMEM201 TMEM31 TMEM51 TMEM60 TMEM79 TNF TNFRSF10C UBIAD1 VAMP1 VAMP4 VAMP5 VMP1 WFDC2 ZDHHC15
Entrez ID		158866	1727
HPRD ID		06758	08942
Ensembl ID		ENSG00000102383	ENSG00000100243
Uniprot IDs		B3KY34 Q96MV8	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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