XCL2 and CCL20

Data Source:
BioGRID (pull down)

		XCL2	CCL20
Description		X-C motif chemokine ligand 2	C-C motif chemokine ligand 20
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity CCR6 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Calcium-mediated Signaling Using Intracellular Calcium Source Defense Response To Bacterium Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS		Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 31959851 30929738 32296059) Asthma (childhood onset) ( 31036433 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood pressure ( 17903302) Crohn's disease ( 26192919) Eating disorders (purging via substances) ( 23568457) Inflammatory bowel disease ( 26192919) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 26192919)
Interacting Genes		19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1	11 interacting genes: CCL5 CCR6 CXCL11 CXCL12 CXCL17 CXCL5 MTDH PF4 TGFB3 VCAN XCL2
Entrez ID		6846	6364
HPRD ID		05317	03571
Ensembl ID		ENSG00000143185	ENSG00000115009
Uniprot IDs		Q9UBD3	P78556
PDB IDs			1M8A 2HCI 2JYO 5UR7 6WWZ
Enriched GO Terms of Interacting Partners?
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