XCL2 and CCL28

Data Source:
BioGRID (pull down)

		XCL2	CCL28
Description		X-C motif chemokine ligand 2	C-C motif chemokine ligand 28
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Exosome
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity
	Biological Process	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Positive Regulation Of Cell-matrix Adhesion Chemotaxis Immune Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Cell Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)	Metabolite levels (X-11787) ( 23934736) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1	26 interacting genes: ACKR2 CCL11 CCL13 CCL17 CCL21 CCL26 CCL5 CCR10 CCR3 CXCL10 CXCL12 CXCL13 CXCL14 CXCL17 CXCL2 CXCL9 DDI1 DYNLT3 PF4 PF4V1 PPBP PSMA3 STUB1 TSC1 XCL1 XCL2
Entrez ID		6846	56477
HPRD ID		05317	05577
Ensembl ID		ENSG00000143185	ENSG00000151882
Uniprot IDs		Q9UBD3	A0N0Q3 D6RC73 Q9NRJ3
PDB IDs			6CWS
Enriched GO Terms of Interacting Partners?
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