XCL2 and CXCL3

Data Source:
BioGRID (pull down)

		XCL2	CXCL3
Description		X-C motif chemokine ligand 2	C-X-C motif chemokine ligand 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Chemokine Activity CXCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)	Inflammatory bowel disease ( 23128233) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1	6 interacting genes: CCL11 CXCL5 CXCL6 CXCR1 CXCR2 XCL2
Entrez ID		6846	2921
HPRD ID		05317	00742
Ensembl ID		ENSG00000143185	ENSG00000163734
Uniprot IDs		Q9UBD3	P19876
PDB IDs
Enriched GO Terms of Interacting Partners?
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