XCL2 and PF4V1

Data Source:
BioGRID (pull down)

		XCL2	PF4V1
Description		X-C motif chemokine ligand 2	platelet factor 4 variant 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space
	Molecular Function	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Blood Circulation Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor	Inflammatory Response Platelet Activation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (q) signalling events	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)	Blood protein levels ( 29875488) Inflammatory bowel disease ( 23128233)
Interacting Genes		19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		6846	5197
HPRD ID		05317	01427
Ensembl ID		ENSG00000143185	ENSG00000109272
Uniprot IDs		Q9UBD3	P10720
PDB IDs			4HSV
Enriched GO Terms of Interacting Partners?
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