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H3-5 and PRMT7
Data Source:
BioGRID
(two hybrid)
H3-5
PRMT7
Description
H3.5 histone
protein arginine methyltransferase 7
Image
No pdb structure
GO Annotations
Cellular Component
Nucleosome
Euchromatin
Nucleus
Fibrillar Center
Nucleus
Nucleoplasm
Cytosol
Molecular Function
Protein Binding
Nucleosomal DNA Binding
Protein Heterodimerization Activity
Protein Binding
Histone-arginine N-methyltransferase Activity
S-adenosylmethionine-dependent Methyltransferase Activity
[myelin Basic Protein]-arginine N-methyltransferase Activity
Protein-arginine Omega-N Monomethyltransferase Activity
Protein-arginine Omega-N Symmetric Methyltransferase Activity
Histone Binding
Ribonucleoprotein Complex Binding
Histone Methyltransferase Activity (H4-R3 Specific)
Biological Process
Positive Regulation Of Cell Growth
Spliceosomal SnRNP Assembly
Regulation Of Gene Expression By Genetic Imprinting
Histone Methylation
Peptidyl-arginine Methylation
Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine
Cell Differentiation
Histone Arginine Methylation
DNA Methylation Involved In Gamete Generation
Regulation Of Protein Binding
Histone H4-R3 Methylation
Pathways
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Birth weight (
31043758
)
Body mass index (
28892062
25673413
)
Magnesium levels (
20700443
)
Offspring birth weight (
31043758
)
Refractive error (
32231278
)
Schizophrenia (
31579629
)
Serum metabolite levels (
23093944
)
Weight (
28552196
)
Interacting Genes
15 interacting genes:
DAXX
DNAJC9
FBLIM1
KAT6A
KDM1A
KDM4B
NASP
NSD3
PRMT5
PRMT6
PRMT7
SETMAR
SMYD1
SMYD3
SUV39H1
13 interacting genes:
CTCFL
DIO3
EIF2S1
H2AC20
H3-5
H3C1
H4C1
MNDA
NFKBID
POT1
SNRPB
ZBTB24
ZNF438
Entrez ID
440093
54496
HPRD ID
18443
15174
Ensembl ID
ENSG00000188375
ENSG00000132600
Uniprot IDs
Q6NXT2
A0A024R726
Q9NVM4
PDB IDs
2PUY
3KV4
4Z5T
5BWN
5BWO
5F6K
5I3L
6OI3
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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