STXBP3 and STXBP2

Data Source:
HPRD (in vivo)

		STXBP3	STXBP2
Description		syntaxin binding protein 3	syntaxin binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse	Extracellular Region Cytosol Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Cytolytic Granule Extracellular Exosome Tertiary Granule Presynapse
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding
	Biological Process	Cellular Glucose Homeostasis Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Brain Development Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma	Leukocyte Mediated Cytotoxicity Platelet Degranulation Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation
Pathways		Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane	Platelet degranulation Other interleukin signaling
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Interacting Genes		14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2
Entrez ID		6814	6813
HPRD ID		10517	03423
Ensembl ID		ENSG00000116266	ENSG00000076944
Uniprot IDs		O00186	Q15833 Q53GF4
PDB IDs			4CCA
Enriched GO Terms of Interacting Partners?
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