STXBP2 and SNRPD3

Data Source:
HPRD (in vitro)

		STXBP2	SNRPD3
Description		syntaxin binding protein 2	small nuclear ribonucleoprotein D3 polypeptide
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Cytolytic Granule Extracellular Exosome Tertiary Granule Presynapse	Commitment Complex Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytosol Nuclear Body Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding	RNA Binding Protein Binding Enzyme Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U7 SnRNA Binding
	Biological Process	Leukocyte Mediated Cytotoxicity Platelet Degranulation Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways		Platelet degranulation Other interleukin signaling	SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Gamma glutamyl transferase levels ( 32084209)
Interacting Genes		13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2	27 interacting genes: CASP8 CLNS1A CRY1 DDX20 GEMIN2 GEMIN5 GEMIN6 GEMIN7 IL12RB1 IL7R LSM3 LSM7 NR1I3 NTAQ1 PRMT5 RBL1 SMN1 SMN2 SNRPB SNRPE SNRPG SREK1 STRAP STXBP2 STXBP3 TRDMT1 WDR77
Entrez ID		6813	6634
HPRD ID		03423	03039
Ensembl ID		ENSG00000076944	ENSG00000100028
Uniprot IDs		Q15833 Q53GF4	P62318
PDB IDs		4CCA	1D3B 3CW1 3JCR 3PGW 3VRI 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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