STXBP3 and DDX20

Data Source:
HPRD (in vivo)

		STXBP3	DDX20
Description		syntaxin binding protein 3	DEAD-box helicase 20
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane Secretory Granule Platelet Alpha Granule Specific Granule Phagocytic Vesicle Extracellular Exosome Tertiary Granule Presynapse	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Protein-containing Complex Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Repressing Transcription Factor Binding
	Biological Process	Cellular Glucose Homeostasis Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Brain Development Vesicle-mediated Transport Protein To Membrane Docking Insulin Secretion Response To Insulin Neutrophil Degranulation Negative Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Glucose Import Platelet Aggregation Cellular Response To Interferon-gamma	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Positive Regulation Of Apoptotic Process Import Into Nucleus
Pathways		Disinhibition of SNARE formation Translocation of SLC2A4 (GLUT4) to the plasma membrane	snRNP Assembly
Drugs
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		14 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 PRKCA RPL3 SMN1 SNRPB SNRPD2 SNRPD3 SNTG1 STX4 STXBP2 VAMP2	32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		6814	11218
HPRD ID		10517	05859
Ensembl ID		ENSG00000116266	ENSG00000064703
Uniprot IDs		O00186	Q9H4N4 Q9UHI6
PDB IDs			2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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