STXBP2 and DDX20

Data Source:
HPRD (in vivo)

		STXBP2	DDX20
Description		syntaxin binding protein 2	DEAD-box helicase 20
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Cytolytic Granule Extracellular Exosome Tertiary Granule Presynapse	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Repressing Transcription Factor Binding
	Biological Process	Leukocyte Mediated Cytotoxicity Platelet Degranulation Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly RNA Processing Positive Regulation Of Apoptotic Process Import Into Nucleus
Pathways		Platelet degranulation Other interleukin signaling	snRNP Assembly
Drugs
Diseases
GWAS			Body mass index ( 29273807) Metabolite levels ( 23823483) Venous thromboembolism ( 32232851)
Interacting Genes		13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2	32 interacting genes: AGO2 APP CRYAB DHX9 ETV3 GEMIN2 GEMIN4 GEMIN5 HDAC2 HDAC5 NCOR1 NCOR2 NR0B2 NUFIP1 PRRC2A RN7SL1 RNU1-1 RNU2-1 SIN3A SMN1 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNUPN STXBP2 STXBP3 TP53
Entrez ID		6813	11218
HPRD ID		03423	05859
Ensembl ID		ENSG00000076944	ENSG00000064703
Uniprot IDs		Q15833 Q53GF4	Q9H4N4 Q9UHI6
PDB IDs		4CCA	2OXC 3B7G
Enriched GO Terms of Interacting Partners?
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