STXBP2 and SNAP23

Data Source:
HPRD (in vivo, in vitro)

		STXBP2	SNAP23
Description		syntaxin binding protein 2	synaptosome associated protein 23
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GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Secretory Granule Specific Granule Azurophil Granule Cytolytic Granule Extracellular Exosome Tertiary Granule Presynapse	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function	Protein Binding Syntaxin-1 Binding Syntaxin Binding Syntaxin-3 Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Leukocyte Mediated Cytotoxicity Platelet Degranulation Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Vesicle-mediated Transport Regulation Of Mast Cell Degranulation Neutrophil Degranulation	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion
Pathways		Platelet degranulation Other interleukin signaling	ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		13 interacting genes: DDX20 GEMIN2 GEMIN4 SMN1 SNAP23 SNRPB SNRPD2 SNRPD3 STX1A STX2 STX3 STXBP3 VAMP2	32 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		6813	8773
HPRD ID		03423	03962
Ensembl ID		ENSG00000076944	ENSG00000092531
Uniprot IDs		Q15833 Q53GF4	A0A024R9R8 A8K287 O00161
PDB IDs		4CCA	1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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