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ELOVL4 and FAXDC2
Data Source:
BioGRID
(two hybrid)
ELOVL4
FAXDC2
Description
ELOVL fatty acid elongase 4
fatty acid hydroxylase domain containing 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Cytoplasm
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
C-4 Methylsterol Oxidase Activity
Iron Ion Binding
Protein Binding
Oxidoreductase Activity
Biological Process
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Positive Regulation Of Protein Phosphorylation
Sterol Biosynthetic Process
Positive Regulation Of Megakaryocyte Differentiation
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Interacting Genes
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
33 interacting genes:
AQP6
ARL13B
CD79A
CGRRF1
CLDN7
CREB3L1
CYB5R3
EBP
ELOVL4
ERGIC3
FCER1G
FFAR2
GOLT1A
GPR152
GPX8
HSD17B13
LMNA
MGST3
NEMP1
PANX1
PGRMC2
RETREG3
SLC10A1
SLC10A6
SLC30A8
STOM
STX4
TMEM106C
TMEM139
TMEM31
TMEM86B
TMPRSS2
TMX2
Entrez ID
6785
10826
HPRD ID
05697
12832
Ensembl ID
ENSG00000118402
ENSG00000170271
Uniprot IDs
Q9GZR5
Q96IV6
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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