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ELOVL4 and SEC22B
Data Source:
BioGRID
(two hybrid)
ELOVL4
SEC22B
Description
ELOVL fatty acid elongase 4
SEC22 homolog B, vesicle trafficking protein
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Golgi Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Synaptic Vesicle
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
Transport Vesicle
COPI-coated Vesicle
Phagocytic Vesicle Membrane
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Melanosome
Molecular Function
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
SNAP Receptor Activity
Protein Binding
Syntaxin Binding
Biological Process
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Protein Transport
Positive Regulation Of Protein Catabolic Process
COPII Vesicle Coating
Vesicle Fusion With Golgi Apparatus
Negative Regulation Of Autophagosome Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways
Synthesis of very long-chain fatty acyl-CoAs
ER-Phagosome pathway
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Iris color (L* coordinate) (
30895295
)
Interacting Genes
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
56 interacting genes:
ABHD16A
AIG1
AQP6
B3GAT3
CD79A
CERS6
CLDN7
CLRN1
CPLX4
CREB3
CREB3L1
DPM3
EBP
ELOVL4
ERGIC3
FAM174A
FAM209A
FCER1G
FNDC9
GJA8
GJB5
GJB6
GORAB
GPR152
GPX8
HIBADH
HSD17B11
HSD17B13
IFNGR2
JAGN1
KIR2DL3
LHFPL1
LHFPL5
LMNA
MFF
MFSD5
MGST2
MGST3
MMGT1
MRPS18B
NDUFAF2
REEP4
RELL2
RHBDD1
SERINC2
SLC35C2
STX1A
STX2
STX4
STX5
TLCD4
TM4SF19
TMEM139
TMEM167B
TMEM229B
TMEM86B
Entrez ID
6785
9554
HPRD ID
05697
04939
Ensembl ID
ENSG00000118402
ENSG00000265808
Uniprot IDs
Q9GZR5
O75396
PDB IDs
2NUP
2NUT
3EGD
3EGX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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