FAXDC2 and TMPRSS2

Data Source:
BioGRID (two hybrid)

		FAXDC2	TMPRSS2
Description		fatty acid hydroxylase domain containing 2	transmembrane serine protease 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Serine-type Endopeptidase Activity Scavenger Receptor Activity Protein Binding Serine-type Peptidase Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Sterol Biosynthetic Process Positive Regulation Of Megakaryocyte Differentiation	Proteolysis Endocytosis Protein Autoprocessing Positive Regulation Of Viral Entry Into Host Cell
Pathways			Attachment and Entry Attachment and Entry Attachment and Entry
Drugs			Camostat
Diseases			Prostate cancer
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Prostate cancer ( 25217961)
Interacting Genes		33 interacting genes: AQP6 ARL13B CD79A CGRRF1 CLDN7 CREB3L1 CYB5R3 EBP ELOVL4 ERGIC3 FCER1G FFAR2 GOLT1A GPR152 GPX8 HSD17B13 LMNA MGST3 NEMP1 PANX1 PGRMC2 RETREG3 SLC10A1 SLC10A6 SLC30A8 STOM STX4 TMEM106C TMEM139 TMEM31 TMEM86B TMPRSS2 TMX2	59 interacting genes: ADIPOQ ANKRD46 AQP1 BMP10 BNIP2 BNIP3 BRICD5 C1QL4 C2CD2L C3orf52 CFHR5 CLEC7A CLK1 CLN6 CMTM7 CNIH2 CNIH3 CTXN3 CXCL9 CYBC1 DEFB103A DEFB103B EDDM3B ERG28 FAM3C FAXDC2 IGFBP5 MOSPD3 NINJ2 PGAP2 PLLP PLN PLP1 PLP2 PTCH1 PTTG1IP SCD SEC22A SELENOK SFTPC SLC35A1 SMIM1 STX7 STX8 TMEM11 TMEM120B TMEM128 TMEM218 TMEM222 TMEM229B TMEM243 TMEM60 TMEM79 TMEM86A TMEM86B TNF UPK2 VAMP5 ZFPL1
Entrez ID		10826	7113
HPRD ID		12832	03637
Ensembl ID		ENSG00000170271	ENSG00000184012
Uniprot IDs		Q96IV6	O15393
PDB IDs
Enriched GO Terms of Interacting Partners?
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