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ELOVL4 and CLCA4
Data Source:
BioGRID
(two hybrid)
ELOVL4
CLCA4
Description
ELOVL fatty acid elongase 4
chloride channel accessory 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Extracellular Region
Plasma Membrane
Integral Component Of Plasma Membrane
Apical Plasma Membrane
Molecular Function
Protein Binding
G Protein-coupled Photoreceptor Activity
Fatty Acid Elongase Activity
3-oxo-arachidoyl-CoA Synthase Activity
3-oxo-cerotoyl-CoA Synthase Activity
3-oxo-lignoceronyl-CoA Synthase Activity
Very-long-chain 3-ketoacyl-CoA Synthase Activity
Intracellular Calcium Activated Chloride Channel Activity
Chloride Channel Activity
Metallopeptidase Activity
Metal Ion Binding
Biological Process
Fatty Acid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Detection Of Visible Light
Fatty Acid Elongation, Saturated Fatty Acid
Sphingolipid Biosynthetic Process
Fatty Acid Elongation, Monounsaturated Fatty Acid
Fatty Acid Elongation, Polyunsaturated Fatty Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Very Long-chain Fatty Acid Biosynthetic Process
Proteolysis
Ion Transmembrane Transport
Chloride Transmembrane Transport
Pathways
Synthesis of very long-chain fatty acyl-CoAs
Stimuli-sensing channels
Drugs
Omega-3-carboxylic acids
Diseases
Stargardt disease (STGD); Fundus flavimaculatus
GWAS
Aging (
22773346
)
Body mass index (
23669352
)
Chronic obstructive pulmonary disease (
28166215
)
Daytime sleep phenotypes (
27126917
)
Macular thickness (
30535121
)
Partial epilepsies (
20522523
)
Interacting Genes
95 interacting genes:
ADGRE2
ANKRD46
APOL3
ATP13A1
BCL2L1
BET1
BIK
BNIP1
BNIP3
BTN2A2
C1GALT1
CCDC167
CCL4L2
CD70
CLCA4
CLDND2
CMTM3
CMTM5
CMTM7
COL4A5
CYB5R3
CYP4F2
ERG28
FA2H
FAM177A1
FAM3C
FAXDC2
FDFT1
FKBP8
FXYD6
GIMAP1
GIMAP5
GOSR2
GPR37L1
GYPA
HMOX1
HMOX2
HSD3B7
IER3IP1
ITGAM
JAGN1
LEPROTL1
LHFPL5
LY6D
MALL
MMP14
NINJ2
ORMDL2
ORMDL3
PKMYT1
PLLP
PLN
PLP1
PTPN1
RAB18
RTP2
SEC22A
SEC22B
SERF1A
SERF1B
SERP2
SFT2D2
SLC30A3
SLC30A8
SNORC
STX3
SYNDIG1
TECR
TF
TMEM11
TMEM128
TMEM19
TMEM199
TMEM203
TMEM218
TMEM222
TMEM242
TMEM243
TMEM254
TMEM42
TMEM44
TRARG1
TREX1
TSNARE1
UBE2J1
UNC50
VAMP1
VAMP3
VAMP4
VAMP5
VAPB
YIF1A
YIPF6
ZDHHC21
ZFPL1
23 interacting genes:
AQP2
BDKRB2
ELOVL4
ERGIC3
FAM209A
FCER1G
FKBP7
GPR42
LMNA
MCFD2
MGST3
PANX1
RETREG3
SCN3B
SLC22A23
SLC35E2A
SLC39A2
SLC39A7
SPN
THAP4
TMEM154
TMEM179B
TMEM51
Entrez ID
6785
22802
HPRD ID
05697
16719
Ensembl ID
ENSG00000118402
ENSG00000016602
Uniprot IDs
Q9GZR5
Q14CN2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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