SULT1E1 and IGSF21

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SULT1E1	IGSF21
Description		sulfotransferase family 1E member 1	immunoglobin superfamily member 21
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Membrane	Adherens Junction Anchored Component Of External Side Of Plasma Membrane Presynaptic Membrane Postsynaptic Membrane Inhibitory Synapse
	Molecular Function	Aryl Sulfotransferase Activity Estrone Sulfotransferase Activity Steroid Binding Protein Binding Sulfotransferase Activity Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity
	Biological Process	Ethanol Catabolic Process Estrogen Catabolic Process Steroid Metabolic Process Estrogen Metabolic Process Positive Regulation Of Fat Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Synapse Maturation
Pathways		Cytosolic sulfonation of small molecules
Drugs		Cyclizine Adenosine 3',5'-diphosphate 3'-phospho-5'-adenylyl sulfate 3,3',5,5'-tetrachlorobiphenyl-4,4'-diol
Diseases
GWAS		Heel bone mineral density ( 30598549)	Atypical femoral fracture in phosphonate treatment ( 31006051) Cobalt levels ( 26025379) Diabetic retinopathy ( 21441570) Erectile dysfunction and prostate cancer treatment ( 20932654) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171) Survival in pancreatic cancer ( 28470677)
Interacting Genes		13 interacting genes: BMPR2 COPS6 EEF1A1 ENOX1 ERG28 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119	32 interacting genes: ALDH2 ANXA3 ATF3 BCR BTBD2 CRCT1 DGKD EPB41L3 ERH ETHE1 GADD45A GIPC2 GSK3B GSTM4 HSPB1 KRAS MAD2L1BP NACA NREP PAEP PAFAH1B3 PCDHA4 PRMT1 PSMD11 RPP14 S100A8 SEPHS1 SERPINB9 SULT1E1 TMSB4X TRBV2 UBE2V2
Entrez ID		6783	84966
HPRD ID		08966	11309
Ensembl ID		ENSG00000109193	ENSG00000117154
Uniprot IDs		P49888 Q53X91	Q96ID5
PDB IDs		1G3M 1HY3 4JVL 4JVM 4JVN
Enriched GO Terms of Interacting Partners?
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