SSBP1 and POLG

Data Source:
HPRD (in vivo)

		SSBP1	POLG
Description		single stranded DNA binding protein 1	DNA polymerase gamma, catalytic subunit
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Nucleoid Mitochondrial Nucleoid Extracellular Exosome	Mitochondrion Gamma DNA Polymerase Complex Protein-containing Complex Mitochondrial Nucleoid Terminal Bouton
	Molecular Function	Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding	Protease Binding DNA Binding Chromatin Binding DNA-directed DNA Polymerase Activity Protein Binding 3'-5' Exonuclease Activity
	Biological Process	Mitochondrial DNA Replication DNA Unwinding Involved In DNA Replication Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis Positive Regulation Of DNA Helicase Activity	DNA Metabolic Process DNA-dependent DNA Replication Mitochondrial DNA Replication Base-excision Repair, Gap-filling Aging Response To Light Stimulus Response To Gamma Radiation Response To Hyperoxia Cellular Response To Glucose Stimulus DNA Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Transcriptional activation of mitochondrial biogenesis
Drugs
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Anorexia nervosa ( 23568457)	Height ( 18193045) Menopause (age at onset) ( 22267201 26414677) Schizophrenia ( 28991256) Smoking status (ever vs never smokers) ( 30643258) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
Interacting Genes		10 interacting genes: CDK1 CKS1B CKS2 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG YWHAQ	2 interacting genes: SSBP1 TTC3
Entrez ID		6742	5428
HPRD ID		02703	01438
Ensembl ID		ENSG00000106028	ENSG00000140521
Uniprot IDs		A4D1U3 B7Z268 Q04837	E5KNU5 P54098
PDB IDs		1S3O 2DUD 3ULL	3IKM 4ZTU 4ZTZ 5C51 5C52 5C53
Enriched GO Terms of Interacting Partners?
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