POLG

Description		DNA polymerase gamma, catalytic subunit
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GO Annotations	Cellular Component	Mitochondrion Gamma DNA Polymerase Complex Protein-containing Complex Mitochondrial Nucleoid Terminal Bouton
	Molecular Function	Protease Binding DNA Binding Chromatin Binding DNA-directed DNA Polymerase Activity Protein Binding 3'-5' Exonuclease Activity
	Biological Process	DNA Metabolic Process DNA-dependent DNA Replication Mitochondrial DNA Replication Base-excision Repair, Gap-filling Aging Response To Light Stimulus Response To Gamma Radiation Response To Hyperoxia Cellular Response To Glucose Stimulus DNA Biosynthetic Process Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Height ( 18193045) Menopause (age at onset) ( 22267201 26414677) Schizophrenia ( 28991256) Smoking status (ever vs never smokers) ( 30643258) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
Interacting Genes		2 interacting genes: SSBP1 TTC3
Entrez ID		5428
HPRD ID		01438
Ensembl ID		ENSG00000140521
Uniprot IDs		E5KNU5 P54098
PDB IDs		3IKM 4ZTU 4ZTZ 5C51 5C52 5C53
Enriched GO Terms of Interacting Partners?
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