SSBP1 and LDB1

Data Source:
HPRD (in vitro)

		SSBP1	LDB1
Description		single stranded DNA binding protein 1	LIM domain binding 1
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Nucleoid Mitochondrial Nucleoid Extracellular Exosome	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex
	Molecular Function	Chromatin Binding Single-stranded DNA Binding RNA Binding Protein Binding	RNA Polymerase II Activating Transcription Factor Binding DNA Binding Chromatin Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association DNA-binding Transcription Factor Binding
	Biological Process	Mitochondrial DNA Replication DNA Unwinding Involved In DNA Replication Mitochondrion Organization Positive Regulation Of Helicase Activity Mitochondrion Morphogenesis Positive Regulation Of DNA Helicase Activity	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Nervous System Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of Cell Migration Regulation Of Transcription Elongation From RNA Polymerase II Promoter Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Mesendoderm Development Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation
Pathways		Transcriptional activation of mitochondrial biogenesis	RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494) Pulse pressure ( 30578418)
Interacting Genes		10 interacting genes: CDK1 CKS1B CKS2 GCM2 LDB1 LGALS7 LGALS7B OTUD6A POLG YWHAQ	32 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IDI2 IRAK3 ISL1 ISL2 LHX1 LHX2 LHX3 LHX4 LHX6 LHX8 LHX9 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP
Entrez ID		6742	8861
HPRD ID		02703	09144
Ensembl ID		ENSG00000106028	ENSG00000198728
Uniprot IDs		A4D1U3 B7Z268 Q04837	A0A6E1WJ75 Q86U70
PDB IDs		1S3O 2DUD 3ULL	2XJY 2XJZ 2YPA 6TYD
Enriched GO Terms of Interacting Partners?
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