SNCB and GRK1

Data Source:
BioGRID (enzymatic study)

		SNCB	GRK1
Description		synuclein beta	G protein-coupled receptor kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus	Photoreceptor Disc Membrane
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity ATP Binding Rhodopsin Kinase Activity
	Biological Process	Chemical Synaptic Transmission Response To Metal Ion Dopamine Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Regulation Of Neuron Death	Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Autophosphorylation
Pathways		MTF1 activates gene expression	Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs
Diseases		Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)	Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS
Interacting Genes		13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA	9 interacting genes: ADRB2 CALM1 CAV1 PDE6D RCVRN RHO SNCA SNCB SNCG
Entrez ID		6620	6011
HPRD ID		03980	01585
Ensembl ID		ENSG00000074317	ENSG00000185974
Uniprot IDs		G4Y815 G4Y816 Q16143	Q15835
PDB IDs			5AFP
Enriched GO Terms of Interacting Partners?
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