SNCB and CENPT

Data Source:
HPRD (two hybrid)

		SNCB	CENPT
Description		synuclein beta	centromere protein T
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Inclusion Body Neuronal Cell Body Axon Terminus	Chromosome, Centromeric Region Kinetochore Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body
	Molecular Function	Phospholipase Inhibitor Activity Calcium Ion Binding Protein Binding Transition Metal Ion Binding Cuprous Ion Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Chemical Synaptic Transmission Response To Metal Ion Dopamine Metabolic Process Negative Regulation Of Catalytic Activity Negative Regulation Of Neuron Apoptotic Process Synaptic Vesicle Endocytosis Synapse Organization Regulation Of Neuron Death	Mitotic Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Chromosome Organization Cell Division Kinetochore Assembly Protein Localization To Kinetochore Involved In Kinetochore Assembly
Pathways		MTF1 activates gene expression	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases		Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
GWAS			Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		13 interacting genes: AKT1 APP CENPT GRK1 GRK5 GRK6 HSPA1A LNX1 MORN4 PLK1 PLK3 SEPTIN4 SNCA	8 interacting genes: APP CENPW COPS5 DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID		6620	80152
HPRD ID		03980	07811
Ensembl ID		ENSG00000074317	ENSG00000102901
Uniprot IDs		G4Y815 G4Y816 Q16143	B3KPB2 Q96BT3
PDB IDs
Enriched GO Terms of Interacting Partners?
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