GRK1 and RCVRN

Data Source:
HPRD (in vitro)

		GRK1	RCVRN
Description		G protein-coupled receptor kinase 1	recoverin
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GO Annotations	Cellular Component	Photoreceptor Disc Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Membrane Dendrite Perikaryon
	Molecular Function	Protein Kinase Activity G Protein-coupled Receptor Kinase Activity ATP Binding Rhodopsin Kinase Activity	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity
	Biological Process	Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Protein Autophosphorylation	Signal Transduction Visual Perception Phototransduction Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade	Inactivation, recovery and regulation of the phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade
Drugs			Myristic acid
Diseases		Congenital stationary night blindness (CSNB), including: CSNB type 1 (CSNB1); CSNB type 2 (CSNB2); CSNB autosomal dominant (CSNBAD); Oguchi disease/ CSNB Oguchi type (CSNBO)
GWAS
Interacting Genes		9 interacting genes: ADRB2 CALM1 CAV1 PDE6D RCVRN RHO SNCA SNCB SNCG	11 interacting genes: CAV1 GIT2 GRK1 GRK2 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1
Entrez ID		6011	5957
HPRD ID		01585	01558
Ensembl ID		ENSG00000185974	ENSG00000109047
Uniprot IDs		Q15835	P35243
PDB IDs		5AFP	2D8N
Enriched GO Terms of Interacting Partners?
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