CPEB1 and KIF1B

Data Source:
HPRD (in vivo, in vitro)

		CPEB1	KIF1B
Description		cytoplasmic polyadenylation element binding protein 1	kinesin family member 1B
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Dendrite Neuron Projection Synapse Messenger Ribonucleoprotein Complex	Mitochondrion Kinesin Complex Microtubule Microtubule Associated Complex Synaptic Vesicle Axon Dendrite Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Axon Cytoplasm
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding MRNA 3'-UTR Binding Protein Binding Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Metal Ion Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity Kinesin Binding Kinase Binding Scaffold Protein Binding
	Biological Process	MRNA Processing Translation Cellular Response To Insulin Stimulus Cellular Response To Amino Acid Stimulus Cellular Response To Hypoxia Positive Regulation Of MRNA Polyadenylation Negative Regulation Of Cytoplasmic Translation	Apoptotic Process Microtubule-based Movement Neuron-neuron Synaptic Transmission Neuromuscular Synaptic Transmission Anterograde Axonal Transport Positive Regulation Of Gene Expression Vesicle-mediated Transport Cytoskeleton-dependent Intracellular Transport Lysosome Localization Response To Rotenone Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport Cellular Response To Nerve Growth Factor Stimulus Protein Localization To Cell Periphery
Pathways			COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases			Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Excessive daytime sleepiness ( 27992416) General cognitive ability ( 29844566) Schizophrenia ( 28991256 30285260) Tourette syndrome ( 30818990)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Hand grip strength ( 29691431) Hematocrit ( 27863252) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Hepatocellular carcinoma ( 20676096) Lateral orbital frontal cortex volume ( 31530798) Mean platelet volume ( 22139419 32888494 27863252) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 18997785) Neutrophil count ( 32888494) Platelet count ( 32888494) Virologic severity in Herpes simplex virus type 2 infection ( 29535370) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: APP DYNLRB1 KIF1B MAP2 PIN1 SLC16A7	22 interacting genes: ARHGAP1 BRCA1 CALM1 CHP1 CLIP4 CPEB1 DLG1 DLG2 DLG3 DLG4 DYSF EEF1A1 GIPC1 LAMTOR5 PATJ PGM1 POMP SIAH1 SNTA1 STARD13 TRIM55 YWHAG
Entrez ID		64506	23095
HPRD ID		09553	05818
Ensembl ID		ENSG00000214575	ENSG00000054523
Uniprot IDs		B4DWY2 Q9BZB8	O60333
PDB IDs		2M13 2MKE 2MKH 2MKK 2N1O	2EH0
Enriched GO Terms of Interacting Partners?
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