CPEB1 and MAP2

Data Source:
HPRD (in vitro, in vivo)

		CPEB1	MAP2
Description		cytoplasmic polyadenylation element binding protein 1	microtubule associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Membrane Dendrite Neuron Projection Synapse Messenger Ribonucleoprotein Complex	Cytoplasm Cytosol Microtubule Microtubule Associated Complex Dendrite Dendrite Cytoplasm Neuron Projection Neuronal Cell Body Axon Initial Segment Dendritic Shaft Axon Hillock Dendritic Growth Cone Main Axon Dendritic Branch Basal Dendrite Primary Dendrite Distal Dendrite Apical Distal Dendrite Dendritic Filopodium Proximal Dendrite Proximal Neuron Projection
	Molecular Function	Translation Repressor Activity, MRNA Regulatory Element Binding MRNA 3'-UTR Binding Protein Binding Translation Factor Activity, RNA Binding MRNA 3'-UTR AU-rich Region Binding Ribosome Binding Metal Ion Binding	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding Tau Protein Binding
	Biological Process	MRNA Processing Translation Cellular Response To Insulin Stimulus Cellular Response To Amino Acid Stimulus Cellular Response To Hypoxia Positive Regulation Of MRNA Polyadenylation Negative Regulation Of Cytoplasmic Translation	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Dendrite Development Central Nervous System Neuron Development Negative Regulation Of Axon Extension Regulation Of Microtubule Polymerization Negative Regulation Of Microtubule Polymerization Neuron Projection Development Dendrite Morphogenesis Positive Regulation Of Anterograde Dense Core Granule Transport Regulation Of Organelle Transport Along Microtubule Positive Regulation Of Anterograde Synaptic Vesicle Transport Regulation Of Cellular Protein Localization Negative Regulation Of Microtubule Binding Negative Regulation Of Microtubule Motor Activity
Pathways
Drugs			Estramustine Paclitaxel Docetaxel
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Excessive daytime sleepiness ( 27992416) General cognitive ability ( 29844566) Schizophrenia ( 28991256 30285260) Tourette syndrome ( 30818990)	Adventurousness ( 30643258) Bipolar disorder ( 31043756) Body mass index ( 28552196) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Handedness (Left-handed vs. non-left-handed) ( 31504236 30980028) Handedness (left-handed vs. right-handed) ( 31504236) Height ( 28552196) Left-handedness ( 32989287) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		6 interacting genes: APP DYNLRB1 KIF1B MAP2 PIN1 SLC16A7	25 interacting genes: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MDM2 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		64506	4133
HPRD ID		09553	01140
Ensembl ID		ENSG00000214575	ENSG00000078018
Uniprot IDs		B4DWY2 Q9BZB8	A0A024R3Y8 A0A024R3Z1 A0A024R409 P11137 Q6NYC5
PDB IDs		2M13 2MKE 2MKH 2MKK 2N1O
Enriched GO Terms of Interacting Partners?
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