RBSN and DNAJC5

Data Source:
BioGRID (fluorescent resonance energy transfer)

		RBSN	DNAJC5
Description		rabenosyn, RAB effector	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS			Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)
Interacting Genes		14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		64145	80331
HPRD ID		15732	08539
Ensembl ID		ENSG00000131381	ENSG00000101152
Uniprot IDs		A8K5H3 Q9H1K0	Q6AHX3 Q9H3Z4
PDB IDs		1YZM 1Z0J 1Z0K	2N04 2N05
Enriched GO Terms of Interacting Partners?
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