RBSN and VPS45

Data Source:
HPRD (in vitro)

		RBSN	VPS45
Description		rabenosyn, RAB effector	vacuolar protein sorting 45 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	Molecular_function Protein Binding
	Biological Process	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)
Interacting Genes		14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18
Entrez ID		64145	11311
HPRD ID		15732	10301
Ensembl ID		ENSG00000131381	ENSG00000136631
Uniprot IDs		A8K5H3 Q9H1K0	A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7
PDB IDs		1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?
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