DNAJC5 and SLC32A1

Data Source:
BioGRID (fluorescent resonance energy transfer, affinity chromatography technology, imaging technique)

		DNAJC5	SLC32A1
Description		DnaJ heat shock protein family (Hsp40) member C5	solute carrier family 32 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Membrane Anchored Component Of Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Chromaffin Granule Membrane Intracellular Membrane-bounded Organelle Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Plasma Membrane Integral Component Of Synaptic Vesicle Membrane Dendrite Synaptic Vesicle Membrane Neuron Projection Intracellular Organelle Dendrite Terminus Neuron Projection Terminus Cone Cell Pedicle Presynaptic Active Zone Cell Tip Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane GABA-ergic Synapse
	Molecular Function	Protein Binding ATP-dependent Protein Binding	Amino Acid Transmembrane Transporter Activity Glycine Transmembrane Transporter Activity Gamma-aminobutyric Acid:proton Symporter Activity
	Biological Process	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle	Amino Acid Transmembrane Transport Ion Transport Neurotransmitter Secretion Aging Gamma-aminobutyric Acid Transport Glycine Transport Hippocampus Development Neurotransmitter Loading Into Synaptic Vesicle
Pathways		Neutrophil degranulation GABA synthesis, release, reuptake and degradation	Transport of inorganic cations/anions and amino acids/oligopeptides GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Immature fraction of reticulocytes ( 32888494) Mean platelet volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate cancer ( 23535732)	circulating leptin levels ( 26833098) circulating leptin levels adjusted for BMI ( 26833098) Schizophrenia ( 25056061 29483656)
Interacting Genes		56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7	2 interacting genes: DNAJC5 F2RL1
Entrez ID		80331	140679
HPRD ID		08539	18058
Ensembl ID		ENSG00000101152	ENSG00000101438
Uniprot IDs		Q6AHX3 Q9H3Z4	Q9H598
PDB IDs		2N04 2N05
Enriched GO Terms of Interacting Partners?
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