RBSN and RAB4A

Data Source:
HPRD (in vivo, in vitro)

		RBSN	RAB4A
Description		rabenosyn, RAB effector	RAB4A, member RAS oncogene family
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GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Zinc Ion Binding	ATPase Activator Activity GTPase Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding
	Biological Process	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization	Phosphatidylinositol Biosynthetic Process Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Positive Regulation Of ATPase Activity
Pathways		Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production	Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling
Drugs
Diseases
GWAS			Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)
Interacting Genes		14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45	33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830
Entrez ID		64145	5867
HPRD ID		15732	01541
Ensembl ID		ENSG00000131381	ENSG00000168118
Uniprot IDs		A8K5H3 Q9H1K0	A0A024R3U9 A0A087WYT5 P20338
PDB IDs		1YZM 1Z0J 1Z0K	1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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