VPS45 and RBSN

Data Source:
HPRD (in vitro)

		VPS45	RBSN
Description		vacuolar protein sorting 45 homolog	rabenosyn, RAB effector
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cellular_component Golgi Apparatus Endosome Membrane Integral Component Of Membrane	Endosome Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Blood Coagulation Vesicle-mediated Transport	Blood Coagulation Protein Transport Endosomal Transport Early Endosome To Golgi Transport Golgi To Lysosome Transport Regulation Of Golgi Organization
Pathways		Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production	Toll Like Receptor 9 (TLR9) Cascade Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)
Interacting Genes		11 interacting genes: BCAR3 CASP8 IGF1R PAX2 PTPN1 RB1CC1 RBSN SNTG1 STX16 VPS11 VPS18	14 interacting genes: AGTR1 DISC1 DNAJC5 DTNBP1 EHD1 EHD2 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		11311	64145
HPRD ID		10301	15732
Ensembl ID		ENSG00000136631	ENSG00000131381
Uniprot IDs		A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7	A8K5H3 Q9H1K0
PDB IDs			1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?
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