SEMG2 and TGM1

Data Source:
HPRD (in vitro)

		SEMG2	TGM1
Description		semenogelin 2	transglutaminase 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Extracellular Exosome	Cornified Envelope Cytosol Plasma Membrane Membrane Intrinsic Component Of Membrane Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Zinc Ion Binding	Protein-glutamine Gamma-glutamyltransferase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Antibacterial Humoral Response Sperm Capacitation Coagulation Positive Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Flagellated Sperm Motility	Cellular Protein Modification Process Positive Regulation Of Keratinocyte Proliferation Peptide Cross-linking Protein Phosphopantetheinylation Keratinocyte Differentiation Cell Envelope Organization Positive Regulation Of Cell Cycle Cornification
Pathways			Formation of the cornified envelope
Drugs		Zinc chloride Zinc sulfate, unspecified form
Diseases			Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Asthma ( 29273806) Bipolar disorder ( 31043756) Blood protein levels ( 28240269) Malaria ( 31844061)
Interacting Genes		8 interacting genes: KLK2 KLK3 PRKAR2A PRKCA PTPRF SEMG1 SERPINA5 TGM1	34 interacting genes: ACADL ALPP C1QTNF1 CNNM3 CRCT1 CXCL16 DOCK2 GSTP1 HSPB1 IFI30 IGSF8 ITGB4 JOSD1 KRTAP4-12 KRTAP5-9 LCE1B LCE1E LCE3A LCE4A MDK MYPOP NECTIN2 NUBP2 PLAAT4 RIN3 SCARF1 SEMG1 SEMG2 SNCA SULT4A1 TACC2 TRAPPC14 VASN VSTM4
Entrez ID		6407	7051
HPRD ID		01642	01824
Ensembl ID		ENSG00000124157	ENSG00000092295
Uniprot IDs		Q02383	P22735
PDB IDs			2XZZ
Enriched GO Terms of Interacting Partners?
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