ABHD4 and PLIN3

Data Source:
BioGRID (two hybrid)

		ABHD4	PLIN3
Description		abhydrolase domain containing 4, N-acyl phospholipase B	perilipin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Membrane Lipid Droplet	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle
	Molecular Function	Lysophospholipase Activity Protein Binding Hydrolase Activity Lysophosphatidic Acid Acyltransferase Activity Carboxylic Ester Hydrolase Activity	Protein Binding Cadherin Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling Lipid Homeostasis N-acylphosphatidylethanolamine Metabolic Process	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage
Pathways		Acyl chain remodelling of PE	Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle
Drugs			Idursulfase Galsulfase
Diseases
GWAS		Metabolite levels ( 23823483) Microalbuminuria ( 26631737)	Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)
Interacting Genes		14 interacting genes: AURKAIP1 BNIP2 CMTM5 COL4A5 CSNK2B DERL1 DGAT2L6 HTATIP2 IGFBP5 INSIG2 PLIN3 RABAC1 REEP5 TK1	32 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C
Entrez ID		63874	10226
HPRD ID		12406	04080
Ensembl ID		ENSG00000100439	ENSG00000105355
Uniprot IDs		Q8TB40	A0A140VJN8 O60664
PDB IDs
Enriched GO Terms of Interacting Partners?
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