PLIN3 and TMEM14C

Data Source:
BioGRID (two hybrid)

		PLIN3	TMEM14C
Description		perilipin 3	transmembrane protein 14C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle	Mitochondrial Inner Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Cadherin Binding	Protein Binding
	Biological Process	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Regulation Of Heme Biosynthetic Process
Pathways		Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle
Drugs		Idursulfase Galsulfase
Diseases
GWAS		Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)	Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		32 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C	45 interacting genes: ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SDC3 SLC10A6 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27
Entrez ID		10226	51522
HPRD ID		04080	15524
Ensembl ID		ENSG00000105355	ENSG00000111843
Uniprot IDs		A0A140VJN8 O60664	A0A024R001 Q9P0S9
PDB IDs			2LOS
Enriched GO Terms of Interacting Partners?
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