PLIN3 and PTPN9

Data Source:
BioGRID (two hybrid)

		PLIN3	PTPN9
Description		perilipin 3	protein tyrosine phosphatase non-receptor type 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle	Nucleoplasm Cytoplasm Neuron Projection Terminus
	Molecular Function	Protein Binding Cadherin Binding	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage	Protein Dephosphorylation Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle	Interleukin-37 signaling
Drugs		Idursulfase Galsulfase
Diseases
GWAS		Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)	Estimated glomerular filtration rate ( 31015462) Height ( 25429064 31562340 20189936) Type 2 diabetes ( 30297969)
Interacting Genes		32 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C	46 interacting genes: AGTRAP AQP6 ARL13B ARL6IP1 ATP5PF BSND CCR2 CDR1 CERS4 CMTM4 CMTM5 COQ3 CPLX4 CREB3 CREB3L1 DERL2 EBP FAM114A2 FKBP7 GET1 GHR GJB1 GORAB HSD17B11 HSD17B13 LIME1 LMNA MAL2 NSF PBX3 PEX12 PLIN3 REEP6 RTN3 SCAMP1 SLC16A13 SLC30A8 SLC7A1 SPAG4 STX6 SYP TMCO2 TMEM80 TMEM86B TMX2 YIF1A
Entrez ID		10226	5780
HPRD ID		04080	02864
Ensembl ID		ENSG00000105355	ENSG00000169410
Uniprot IDs		A0A140VJN8 O60664	P43378 Q6IQ43
PDB IDs			2PA5 4GE2 4GE5 4GE6 4ICZ 6KZQ 6L03
Enriched GO Terms of Interacting Partners?
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