SCNN1D and SCNN1B

Data Source:
HPRD (in vivo)

		SCNN1D	SCNN1B
Description		sodium channel epithelial 1 subunit delta	sodium channel epithelial 1 subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Actin Cytoskeleton Membrane Sodium Channel Complex	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Sodium Ion Transport Ion Transmembrane Transport Sodium Ion Transmembrane Transport Response To Stimulus Sensory Perception Of Taste	Sodium Ion Transport Excretion Gene Expression Artery Smooth Muscle Contraction Ion Transmembrane Transport Sodium Ion Transmembrane Transport Epithelial Fluid Transport Response To Drug Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Sodium Ion Homeostasis Cellular Response To Aldosterone
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases			Liddle syndrome Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Bronchiectasis with or without elevated sweat chloride
GWAS		Inflammatory bowel disease ( 28067908) Platelet count ( 24777453) Ulcerative colitis ( 28067908)	Kidney stones ( 31729369)
Interacting Genes		2 interacting genes: SCNN1B SCNN1G	14 interacting genes: ANK3 CNTN1 COMMD10 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2
Entrez ID		6339	6338
HPRD ID		03209	02861
Ensembl ID		ENSG00000162572	ENSG00000168447
Uniprot IDs		P51172	B2R812 P51168
PDB IDs			6BQN 6WTH
Enriched GO Terms of Interacting Partners?
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