SCNN1D and SCNN1G

Data Source:
HPRD (in vivo)

		SCNN1D	SCNN1G
Description		sodium channel epithelial 1 subunit delta	sodium channel epithelial 1 subunit gamma
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Actin Cytoskeleton Membrane Sodium Channel Complex	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Exosome Plasma Membrane Protein Complex
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity	Ion Channel Activity Sodium Channel Activity Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding
	Biological Process	Sodium Ion Transport Ion Transmembrane Transport Sodium Ion Transmembrane Transport Response To Stimulus Sensory Perception Of Taste	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Sensory Perception Of Taste Sodium Ion Homeostasis Cellular Response To Aldosterone
Pathways		Stimuli-sensing channels	Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases			Liddle syndrome Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome) Bronchiectasis with or without elevated sweat chloride
GWAS		Inflammatory bowel disease ( 28067908) Platelet count ( 24777453) Ulcerative colitis ( 28067908)	Heel bone mineral density ( 30598549) Parent of origin effect on receptive language ability (paternal) ( 32635940)
Interacting Genes		2 interacting genes: SCNN1B SCNN1G	13 interacting genes: COMMD10 EPN1 MAPK1 NEDD4 NEDD4L SCNN1A SCNN1B SCNN1D SERP1 SOX4 STX1A USP10 WWP2
Entrez ID		6339	6340
HPRD ID		03209	02862
Ensembl ID		ENSG00000162572	ENSG00000166828
Uniprot IDs		P51172	A5X2V1 P51170
PDB IDs			6BQN 6WTH
Enriched GO Terms of Interacting Partners?
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