ABCE1 and EIF3J

Data Source:
BioGRID (two hybrid)

		ABCE1	EIF3J
Description		ATP binding cassette subfamily E member 1	eukaryotic translation initiation factor 3 subunit J
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	Iron Ion Binding Protein Binding ATP Binding ATPase Activity Ribosomal Small Subunit Binding Endoribonuclease Inhibitor Activity	Translation Initiation Factor Activity Protein Binding Identical Protein Binding
	Biological Process	Ribosomal Subunit Export From Nucleus Translational Initiation Translational Termination Viral Process Defense Response To Virus Regulation Of Type I Interferon-mediated Signaling Pathway Negative Regulation Of Endoribonuclease Activity	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation
Pathways		OAS antiviral response Interferon alpha/beta signaling	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Malaria ( 31844061) Subcortical volume (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		3 interacting genes: EIF3J RNASE2 RNASEL	15 interacting genes: ABCE1 CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1
Entrez ID		6059	8669
HPRD ID		03132	04883
Ensembl ID		ENSG00000164163	ENSG00000104131
Uniprot IDs		P61221	A0A024R5S5 O75822
PDB IDs		6ZME 6ZVJ 7A09	2KRB 3BPJ 6YBW 6ZMW 6ZVJ
Enriched GO Terms of Interacting Partners?
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